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Kamel Khalili — Dr. Kamel Khalili's lab is focused on finding a cure for HIV using advanced gene editing technologies, specifically CRISPR. The lab aims to enhance the immune response and eliminate the HIV virus that remains hidden in the body despite treatment. Through innovative research and collaboration, they are developing targeted therapies that could lead to sustainable control or elimination of the virus.
Yuri Persidsky — Dr. Yuri Persidsky's lab focuses on how substances like alcohol and electronic cigarettes can damage the blood-brain barrier and lung functions. They study what happens at the cellular level during this damage and explore potential therapeutic interventions. Their work is crucial for understanding the long-term effects of these substances, particularly in adolescents, who are significant users of e-cigarettes.
Mary F Barbe — Dr. Mary F. Barbe's lab explores the causes and recovery strategies for musculoskeletal injuries that arise from repetitive overuse. The research focuses on how factors such as sleep quality, inflammation, and fibrosis (scar tissue formation) contribute to pain and dysfunction, particularly as these factors may differ with age and between sexes. The lab tests non-pharmacological interventions like improved sleep and aerobic exercise to see how they can aid recovery in rat models of injury.
Mohammad F Kiani — Dr. Mohammad F Kiani's lab at Temple University focuses on developing innovative solutions for treating radiation-induced injuries, particularly to the vascular system. Using cutting-edge microphysiological models, the lab aims to understand how radiation exposure affects blood vessel function and immune cell interactions. The ultimate goal is to identify and repurpose existing FDA-approved drugs that could help mitigate the harmful effects of radiation on health.
Tania Giovannetti — Dr. Tania Giovannetti's lab focuses on improving the assessment of everyday functioning in older adults, particularly those at risk for cognitive decline and Alzheimer's disease. They utilize innovative digital tools, such as virtual reality and smartphone applications, to create more accurate and efficient measures of functional abilities over time. This research aims to pave the way for better clinical evaluations and interventions that can support aging populations.
Mathieu Wimmer — Dr. Mathieu Wimmer's lab explores how early life experiences, particularly resource scarcity, shape brain function and behavior. Using rat models, the research investigates the molecular and neural changes that affect reward processing and motivation, which are important for understanding substance use disorders. The lab's work has the potential to inform new strategies for prevention and treatment by identifying how early life conditions contribute to mental health challenges.
Laurie E Kilpatrick — Dr. Laurie E Kilpatrick's lab focuses on understanding how different types of immune cells, specifically neutrophils, contribute to sepsis, a life-threatening condition caused by infection. The lab uses innovative techniques like 'organ-on-chip' technology to model human responses and characterize neutrophil behavior, aiming to develop targeted treatments for sepsis based on individual patient profiles. By linking immune cell characteristics to clinical outcomes, the research aims to improve therapies for this critical condition.
David Victor Smith — Dr. David Victor Smith leads a research lab at Temple University focused on understanding how social and cognitive factors influence financial decision-making in older adults, particularly those at risk for Alzheimer's Disease and related dementias. The lab investigates how brain activity related to social rewards and finance differs across ages and cognitive states, with the goal of identifying vulnerable individuals who might be at risk for financial exploitation. Ultimately, this research seeks to improve protective measures for older adults against financial fraud.