Loading labs
Searching…
5,323 labs
Steven L. Salzberg — Dr. Steven Salzberg's lab at Johns Hopkins University focuses on developing advanced computational methods to analyze and interpret genomic data. By creating new tools and databases, the lab aims to enhance our understanding of human and other genomes, improving gene discovery and genome annotation processes. This research is essential for addressing genetic diseases and expanding the knowledge of biological diversity.
Richard A Gibbs — The lab led by Richard A. Gibbs at Baylor College of Medicine focuses on understanding genetic variations that contribute to various rare diseases. Through advanced genomic sequencing techniques and a large-scale network of collaborations, the lab enrolls families with difficult-to-diagnose conditions and aims to uncover the genetic causes behind these issues. By utilizing cutting-edge technology and rigorous data analysis, the lab works not only on individual cases but also on population-scale genomic studies to enhance diagnosis and treatment strategies.
Yan Cui — Dr. Yan Cui's research lab focuses on understanding how a specific pathway in the immune system affects head and neck cancers, particularly those that arise due to tobacco and alcohol use. The team studies how certain molecules in the tumor environment, like CD73 and its receptor A2BR, help tumors evade the immune system, making them harder to treat. By exploring these interactions, the lab aims to develop new therapies that can enhance immune responses against these aggressive cancers.
Charles M Perou — Dr. Charles M. Perou's lab at the University of North Carolina Chapel Hill focuses on understanding how breast cancer cells spread to different organs in the body. By studying the molecular and cellular mechanisms involved in this process, particularly in various subtypes of breast cancer, the lab aims to identify why certain tumors prefer to metastasize to certain organs. The research combines data from human samples and mouse models with advanced techniques to uncover potential new treatments for metastatic breast cancer.
David H Haussler — Dr. David Haussler's lab at UC Santa Cruz focuses on creating innovative methods for studying live cells and tissues to better understand neurodevelopment and pediatric cancers. By developing cost-effective, customizable experimental platforms that allow remote control of live cell cultures, the lab aims to make significant strides in genomic research and education. The lab also emphasizes inclusive training programs, helping students from diverse backgrounds gain valuable skills in genomic science and lab techniques.
Jeffrey I Gordon — Dr. Jeffrey I. Gordon's lab focuses on understanding how gut microbes influence the health and development of children, particularly those suffering from malnutrition. The lab has developed innovative food formulations designed to improve gut microbiota in undernourished children, which helps enhance their growth and overall health. By studying the relationship between specific dietary components and gut bacteria, they aim to create effective nutritional strategies that promote better developmental outcomes.
John Morris — Dr. John Morris's lab at Washington University focuses on understanding Alzheimer's disease by investigating early biomarkers in middle-aged individuals, especially those with a family history of the disease. The lab studies how changes in the brain can indicate the potential onset of Alzheimer's, even before symptoms appear. Through various projects, they explore factors that may influence the progression from preclinical conditions to symptomatic Alzheimer's while examining biological tests and lifestyle factors that may impact brain health.
Richard A Flavell — Dr. Richard Flavell's lab at Yale University focuses on studying Alcoholic Liver Disease (ALD), particularly Alcohol Associated Hepatitis (AAH), using advanced humanized mouse models. These models mimic human liver conditions better than traditional mouse models, allowing researchers to explore cellular interactions and metabolic changes in the liver that contribute to disease. The lab aims to uncover how specific signaling interactions between liver cells and immune cells are involved in AAH to identify potential treatment targets.
Liang Li — Dr. Liang Li's lab focuses on understanding and treating diseases affecting the exocrine pancreas, particularly chronic pancreatitis and its serious complications, such as diabetes and pancreatic cancer. The lab works on collecting and analyzing clinical data to support the development of new therapies and biomarkers, which can enhance patient care and disease understanding. Collaborating with a network of clinical researchers, they aim to improve patient outcomes through comprehensive studies.
Terrie E Moffitt — Terrie E Moffitt's lab at Duke University focuses on understanding biological aging through a novel measurement tool called DunedinPoAm4x. By analyzing blood samples and studying numerous physiological biomarkers over decades, the lab aims to pinpoint how quickly individuals age biologically compared to their chronological age. Their research seeks to improve aging assessments and explore how lifestyle changes and genetic factors can influence the pace of aging.