Temple University · BiologyMusculoskeletal Recovery and Resilience Lab
Mary F Barbe · Philadelphia, Pennsylvania
Research Focus
Dr. Mary F. Barbe's lab explores the causes and recovery strategies for musculoskeletal injuries that arise from repetitive overuse. The research focuses on how factors such as sleep quality, inflammation, and fibrosis (scar tissue formation) contribute to pain and dysfunction, particularly as these factors may differ with age and between sexes. The lab tests non-pharmacological interventions like improved sleep and aerobic exercise to see how they can aid recovery in rat models of injury.
musculoskeletal injuriessleep qualityfibrosisaerobic exercisechronic paininflammationgender differencesaging
Research Aims
5AIM 01Determine causal pathways in overuse musculoskeletal injuries in young adult rats.
AIM 02Investigate the role of sleep in moderating pain intensity and persistence.
AIM 03Assess the efficacy of improved sleep and aerobic exercise in enhancing recovery.
AIM 04Examine the effects of aging on the risk of pain and recovery following overuse injuries.
AIM 05Evaluate the combined impact of reduced fibrosis and enhanced sleep/exercise on neuromuscular function.
Skills the Lab Values
animal handlingrat modelsexercise physiologytissue inflammation assessmentpain measurement techniquesanti-fibrotic treatment administrationdata collection and analysisexperimental designbehavioral testing
Output against the department
Publications457top 9% of dept.95th of 1,033
this lab
most publishedleast published
Citations10ktop 37% of dept.381st of 1,033
this lab
most citedleast cited
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