Temple University · PsychologyCenter for Early Life Neuroscience
Mathieu Wimmer · Philadelphia, Pennsylvania
Research Focus
Dr. Mathieu Wimmer's lab explores how early life experiences, particularly resource scarcity, shape brain function and behavior. Using rat models, the research investigates the molecular and neural changes that affect reward processing and motivation, which are important for understanding substance use disorders. The lab's work has the potential to inform new strategies for prevention and treatment by identifying how early life conditions contribute to mental health challenges.
epigeneticsneurosciencesubstance use disordermotivated behaviorreward processing
Research Aims
5AIM 01Investigate the impact of early life scarcity on reward processing in adult rats.
AIM 02Characterize sex-specific physiological changes in the nucleus accumbens due to early scarcity.
AIM 03Identify molecular mechanisms linking early life experiences to motivated behavior.
AIM 04Examine the influence of environmental factors on substance use disorder risk.
AIM 05Develop insights for prevention and treatment strategies for substance use disorders.
Skills the Lab Values
behavioral assayscell cultureelectrophysiologygene expression analysischromatin remodelinganimal modelsRNA sequencingdata analysisdrug administration techniques
Output against the department
Publications74bottom 18% of dept.242nd of 296
this lab
most publishedleast published
Citations4.1kbottom 39% of dept.181st of 296
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.