John F Hartwig — Professor John F. Hartwig's lab at UC Berkeley focuses on developing innovative chemical reactions that are essential for creating new medications. The lab works with transition metals to discover new catalysts that can streamline the production of important organic compounds, particularly those that target specific parts of complex molecules. This research aims to deepen our understanding of how these catalysts operate, leading to more effective and efficient synthetic methods in medicinal chemistry.
Jay D Keasling — Dr. Jay D. Keasling's lab focuses on developing improved vaccines by designing better adjuvants, which are substances that enhance the immune response to vaccine antigens. The research combines synthetic biology techniques to engineer yeast for adjuvant production with systems immunology to understand how these adjuvants work at the molecular level. This interdisciplinary approach aims to create innovative solutions for preventing and treating diseases.
F. Dean Toste — Dr. F. Dean Toste's lab at UC Berkeley focuses on creating new methods for synthesizing organic compounds that can be used in medicine. The lab mainly develops new reactions using special catalysts to construct important chemical bonds, particularly those involving fluorine. Researchers also investigate how non-covalent interactions influence chemical selectivity, aiming to improve tools for chemists and biomedical researchers.
Chunlei Liu — Dr. Chunlei Liu's lab at UC Berkeley focuses on understanding and manipulating the roles of astrocytes, the brain's most abundant cells, in health and disease. They aim to develop advanced technologies for precise control of calcium signaling in astrocytes, which is crucial for neuronal interactions and brain function. The lab also innovates in MRI technology to enhance imaging capabilities for neurological conditions, including Alzheimer's disease, by creating programmable MRI coils that improve brain imaging and diagnosis.
Richard Ivry — The research lab of Dr. Richard Ivry at UC Berkeley focuses on understanding the cerebellum and its significant role in various cognitive processes beyond just movement control. The lab investigates how the cerebellum contributes to tasks such as perception, attention, and decision-making by conducting behavioral experiments and neuroimaging studies. They also study patients with cerebellar disorders to better understand cognitive impairments related to cerebellar function.
Allison G Harvey — Dr. Allison G Harvey's lab focuses on understanding and improving sleep and circadian functioning in midlife and older adults, as well as in adolescents with evening chronotypes (night-owls). The lab investigates innovative treatments that enhance patient memory for sleep interventions to boost treatment adherence and outcomes. They also explore habit-based interventions to promote better sleep health behaviors among youth, particularly targeting those at risk for various health complications.
Daniel Feldman — Dr. Daniel Feldman's research lab at UC Berkeley focuses on understanding how certain brain cells, called inhibitory interneurons, regulate their activity in response to sensory experiences and learning. The lab investigates how these changes may play a role in conditions like autism, particularly looking at molecular mechanisms and plasticity in different types of interneurons. By studying how these cells can adapt in the somatosensory cortex, the research aims to uncover new therapeutic targets for improving brain function in autism and similar disorders.
Lin He — Dr. Lin He's lab at UC Berkeley studies the role of retrotransposons—genetic elements that can move around within the genome—in mammalian development and reproductive aging. Their research aims to uncover how these elements influence gene regulation during early embryo development and the aging process of female reproductive cells. By using advanced techniques like CRISPR and genomics, the lab investigates the functional significance of retrotransposon-derived promoters and how they can lead to alternative gene forms that impact cell functions.
David G Drubin — David G Drubin's lab at UC Berkeley focuses on understanding how cells take in materials and interact with their environment, particularly through a process called clathrin-mediated endocytosis (CME). They study this process in both yeast and human stem cells, using advanced imaging techniques to look at the proteins involved and how they function together. Their research aims to uncover the mechanisms behind how cells differentiate and respond under various conditions, which could have implications for understanding diseases and developing treatments.