University of California-Berkeley · ChemistryCatalytic Organic Synthesis Group
F. Dean Toste · Berkeley, California
Research Focus
Dr. F. Dean Toste's lab at UC Berkeley focuses on creating new methods for synthesizing organic compounds that can be used in medicine. The lab mainly develops new reactions using special catalysts to construct important chemical bonds, particularly those involving fluorine. Researchers also investigate how non-covalent interactions influence chemical selectivity, aiming to improve tools for chemists and biomedical researchers.
Organic SynthesisCatalysisEnantioselectivityFluorinationTransition MetalsChiral AnionsMechanistic StudiesMedicinal Chemistry
Research Aims
4AIM 01Develop new catalytic methods for selective organic synthesis.
AIM 02Explore enantioselective transformations for medicinal chemistry applications.
AIM 03Investigate the role of non-covalent interactions in chemical selectivity.
AIM 04Create novel fluorinated building blocks for organic synthesis.
Skills the Lab Values
Catalyst DevelopmentOrganic Reaction DesignFluorine ChemistryMechanistic AnalysisData Science TechniquesSynthetic MethodologyAnalytical ChemistryBuilding Block Construction
Output against the department
Publications799top 7% of dept.15th of 216
this lab
most publishedleast published
Citations56ktop 6% of dept.13th of 216
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.