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Akhil B Vaidya — Dr. Akhil B Vaidya's lab at Drexel University focuses on understanding fundamental aspects of malaria parasites, particularly how they maintain sodium and lipid balance, and the roles of mitochondria in their survival. The research aims to uncover how these processes can be disrupted by new drugs to combat malaria, a disease that causes significant global health issues. By investigating the molecular pathways involved, the lab strives to identify new targets for antimalarial drug development.
Meghan Butryn — Dr. Meghan Butryn's lab at Drexel University focuses on cancer prevention through dietary change. The research aims to develop and evaluate interventions that help adults improve their eating habits by promoting nutritious foods and minimizing unhealthy options in their homes. By leveraging support from household members and innovative strategies for motivation, the lab seeks to increase adherence to established dietary guidelines that can lower cancer risk.
Michael R Lowe — Dr. Michael R Lowe's research lab at Drexel University investigates the physiological and psychological factors that contribute to weight regain after weight loss. By studying how metabolic efficiency and appetite influence weight management, the lab aims to improve obesity treatment methods, emphasizing the complexity of maintaining weight loss. Their work includes recruiting participants and analyzing their metabolic responses during and after a structured weight loss program.
Brisa N Sanchez — Dr. Brisa N Sanchez's lab focuses on understanding how nutrition interventions and food environments impact children's health and academic performance, particularly in underrepresented populations. By examining large-scale studies, the lab seeks to identify effective strategies to reduce health disparities related to obesity and education among children. The research aims to inform public health policies and practices that promote healthier lifestyles for children.
Anneclaire J De Roos — Dr. Anneclaire J De Roos's research lab focuses on understanding how extreme weather events, like heatwaves and heavy rainfall, impact children's health. The lab investigates both immediate health effects, such as respiratory issues and injuries, and long-term health problems caused by repeated exposure to extreme weather. They aim to gather data and provide insights that will inform policies to protect vulnerable communities and promote health equity.
Brian Wigdahl — Dr. Brian Wigdahl's lab at Drexel University focuses on developing advanced gene editing strategies to combat HIV-1 infection, particularly in the body's various tissue reservoirs, including the brain. By utilizing CRISPR technology, the lab aims to enhance the precision and effectiveness of treatments targeting the diverse strains of HIV found in patients. Their innovative research combines high-throughput biological assays and computational biology to improve gene editing outcomes, ultimately seeking to provide a potential cure for HIV.
Frank A Ferrone — Dr. Frank Ferrone's lab at Drexel University focuses on understanding sickle cell disease and improving treatments for it. The research aims to uncover how fetal hemoglobin can reduce the harmful effects of sickle hemoglobin, helping to optimize existing gene therapies and discover new drug treatments. By investigating the basic mechanisms of hemoglobin behavior, the lab contributes to better therapeutic strategies for this widespread condition.
Alessandro Fatatis — Dr. Alessandro Fatatis's lab at Drexel University focuses on understanding how certain cancer cells thrive in the harsh environment of metastatic prostate cancer, especially when traditional therapies targeting the Androgen Receptor fail. They explore the role of Interleukin-1beta, a signaling molecule that may help cancer cells survive and spread in bone tissue. Through their research, they aim to uncover new treatment strategies that could complement existing therapies and combat advanced prostate cancer more effectively.
Cameron F Abrams — Dr. Cameron F. Abrams' lab at Drexel University focuses on understanding the conformational changes of the HIV-1 envelope glycoprotein (Env), which plays a critical role in how the virus enters human cells. By combining advanced molecular simulations with biophysical techniques, the lab aims to discover new ways to inhibit the virus and aid in vaccine development. This research is vital for creating effective treatments and vaccines for HIV.