Loading university
Ann C. Mckee — Dr. Ann C. McKee's lab at Boston University focuses on understanding the long-term effects of repetitive head impacts, such as those experienced in sports and military service. The research aims to reveal how these impacts contribute to neurodegenerative diseases like Alzheimer's and chronic traumatic encephalopathy (CTE) over a person's lifespan, particularly emphasizing early-life changes. By studying brain tissue from various age groups, the lab seeks to identify early biomarkers and potential therapeutic targets for these conditions.
David A Boas — Dr. David Boas' lab focuses on understanding how stroke affects brain recovery, specifically how changes in blood flow and blood vessels influence healing. They use advanced imaging techniques to study these processes in animal models of stroke. Ultimately, their research aims to improve treatment and recovery strategies for stroke patients by linking vascular changes to brain function recovery.
Chunyu Liu — Dr. Chunyu Liu's lab at Boston University Medical Campus focuses on understanding how alcohol consumption affects cardiovascular disease through a multi-omic approach. They utilize advanced techniques to analyze DNA, RNA, proteins, and metabolites in relation to alcohol use and its health impacts. By identifying molecular markers associated with alcohol intake, the lab aims to uncover pathways that could lead to better prevention and treatment strategies for cardiovascular disease.
Michael W. Otto — Dr. Michael W. Otto's lab at Boston University focuses on understanding how anxiety disorders respond to exposure-based therapy—a common treatment method. The lab is investigating the potential of measuring carbon dioxide reactivity as a biomarker to predict whether patients will benefit from this therapy. This research aims to improve treatment selection for patients suffering from anxiety-related disorders and enhance the overall effectiveness of mental health interventions.
Mark W. Grinstaff — Dr. Mark W. Grinstaff's lab at Boston University focuses on developing innovative therapeutic strategies to treat cancer and metabolic diseases. Their research is at the intersection of chemistry and biology, utilizing novel biomaterials and RNA technologies to improve drug delivery and efficacy. Key projects include addressing lung cancer through self-amplifying RNA therapies and proposing new treatments for liver disease by restoring lysosome function.
Ji-Xin Cheng — Professor Ji-Xin Cheng's lab at Boston University focuses on developing advanced imaging techniques to tackle pressing health issues, particularly in detecting antimicrobial resistance and understanding cellular processes. They aim to create tools that can quickly identify how bacteria and fungi respond to treatments at the single-cell level, which is vital for improving clinical outcomes. The lab also explores novel microscopy technologies to visualize and understand the molecular mechanisms in living tissues, which could lead to breakthroughs in disease diagnosis and treatment.
Rhoda Au — Dr. Rhoda Au's lab focuses on understanding and preventing Alzheimer's disease through innovative digital technologies. They aim to develop continuous cognitive assessment tools that can detect changes in cognitive health before more severe symptoms emerge. Using data from studies such as the Framingham Heart Study, the lab combines advanced imaging techniques with digital biomarkers to better identify individuals at risk of Alzheimer's and tailor personalized interventions.
Benjamin L Wolozin — Dr. Benjamin Wolozin's lab at Boston University Medical Campus focuses on understanding the role of RNA modifications in Alzheimer's disease and related neurodegenerative disorders. They study how changes in specific RNA molecules can contribute to disease progression and aim to identify novel therapeutic targets that could potentially delay or alter the course of Alzheimer's. Through various experimental approaches, the lab investigates the interplay between RNA biology and the pathophysiological processes underlying neurodegeneration.
Sandor Vajda — Dr. Sandor Vajda's lab at Boston University specializes in the analysis and prediction of molecular interactions, particularly focusing on proteins. The team works on methodologies that combine machine learning with physics-based techniques to improve the accuracy of predicting how proteins and ligands interact. They have achieved notable success in established competitions by enhancing traditional docking methods to better address the challenges posed by limited data.