Boston University · EngineeringTissue Engineering and Vascularization Lab
Christopher S Chen · Boston, Massachusetts
Research Focus
Dr. Christopher S. Chen's lab at Boston University focuses on engineering tissues that can mimic the natural functions of human organs, specifically the liver. The lab studies how cells communicate and work together to create structures, like blood vessels, that are essential for organ health. By developing innovative techniques for controlling cell interactions, this research aims to advance the ability to grow transplantable tissues and understand how cells respond to mechanical forces, which could lead to better healing methods.
tissue engineeringvascularizationcell-cell communicationmechanobiologyliver graftssynthetic biologystem cellscell adhesion
Research Aims
3AIM 01Engineer functional blood vessels in lab-grown liver tissues
AIM 02Investigate how cells communicate and grow in engineered environments
AIM 03Understand how new types of cell connections respond to mechanical forces
Skills the Lab Values
microfluidic device fabricationtissue culturegene editingmechanical testingimmunostaininglive-cell imagingbioinformaticscell signaling assays
Output against the department
Publications714top 5% of dept.14th of 278
this lab
most publishedleast published
Citations68ktop 3% of dept.7th of 278
this lab
most citedleast cited
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