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Melinda Larsen — Dr. Melinda Larsen's lab focuses on understanding and treating fibrosis, particularly in salivary glands damaged by radiation or diseases like Sjogren's Syndrome. They explore how certain cells contribute to fibrosis and investigate potential therapies that could improve organ regeneration. This research is crucial as fibrosis is a major health issue, contributing to significant morbidity and mortality.
Shenglong Zhang — Dr. Shenglong Zhang's lab at the State University of New York at Albany focuses on advancing mass spectrometry techniques to improve the understanding of RNA modifications, which play crucial roles in cellular functions and diseases. The lab aims to develop a next-generation sequencing method that can identify and quantify all RNA modifications at the single nucleotide level, addressing significant gaps in current RNA research.
Annalisa Scimemi — Dr. Annalisa Scimemi's lab studies how specific brain cells, called pyramidal cells, integrate different types of signals in the hippocampus, which is critical for memory and spatial navigation. The lab investigates how a neurotransmitter called glutamate, which is important for communication between neurons, can affect both excitatory and inhibitory signals onto these pyramidal cells. Understanding these mechanisms may help develop new treatments for conditions like epilepsy and autism spectrum disorder.
Betty Lin — Dr. Betty Lin's lab focuses on understanding how stress during pregnancy affects the health of Black mothers and infants. The research explores both the short-term and long-term health consequences of various stress factors, including community and family dynamics. By studying the physiological responses to stress and the impact of paternal support, her lab aims to find ways to improve maternal and infant health outcomes for Black families in the United States.
Andrew Berglund — Dr. Andrew Berglund's lab focuses on developing new small molecule therapeutics to treat neuromuscular and neurodegenerative diseases, particularly myotonic dystrophy and spinocerebellar ataxias. The research aims to understand the mechanisms through which expanded RNA sequences disrupt normal RNA processing and to design drugs that can reduce the toxicity of these expanded RNAs. By utilizing both in vitro and in vivo models, the lab evaluates the efficacy and safety of these compounds, potentially advancing towards future clinical therapies.