Loading university
Ulrich Mueller — Dr. Ulrich Mueller's laboratory at Johns Hopkins University focuses on understanding the function of hair cells in the inner ear, which are critical for hearing. The lab studies specific genes linked to hearing loss and how those genes affect the development and function of these hair cells. Researchers investigate the mechanisms of signal transmission in auditory circuits and the impact of genetic mutations on hearing capability.
Ted M. Dawson — Dr. Ted Dawson's lab at Johns Hopkins focuses on understanding the mechanisms of neurotoxicity related to stroke and neurodegenerative diseases. They investigate a specific form of cell death called parthanatos, particularly how the enzyme associated with it, known as PAAN/MIF, contributes to injury in neurons. The ultimate goal of the research is to develop innovative therapies to protect neurons from damage and improve outcomes for patients suffering from strokes and similar conditions.
Valina L. Dawson — Dr. Valina L. Dawson's lab focuses on understanding the mechanisms underlying neurodegenerative diseases like Parkinson's disease and Alzheimer's disease. By studying the roles of specific proteins and metabolic changes in brain cells, the lab seeks to uncover the causes of cognitive dysfunction and develop potential therapies to protect neurons. Their research uses innovative techniques, including imaging mass spectrometry and genetic models, to explore how changes in brain metabolism affect neurodegeneration.
Arturo Casadevall — Dr. Arturo Casadevall's lab at Johns Hopkins University focuses on understanding the biology of Cryptococcus neoformans, a dangerous fungal pathogen. The lab investigates how this fungus produces melanin, which helps it evade the immune system and resist antifungal treatments. By studying this process, the lab aims to develop new drugs and diagnostic tools to treat infections caused by drug-resistant fungi, ultimately improving health outcomes for people, especially those with weakened immune systems.
Richard L Huganir — Dr. Richard L Huganir's lab at Johns Hopkins University focuses on understanding how the brain encodes memories through the study of AMPA receptors, which are crucial for synaptic transmission and plasticity. The lab uses innovative techniques such as two-photon microscopy and biotinylation to visualize and analyze the interactions of synaptic proteins during learning and memory processes in live mice. Their research aims to uncover the molecular mechanisms underlying various brain disorders and to identify potential therapeutic targets for conditions like Alzheimer's, schizophrenia, and autism.
Michael G. Goggins — Dr. Michael G. Goggins' lab at Johns Hopkins University focuses on improving the early detection and screening of pancreatic cancer, particularly for individuals at high genetic risk. The lab conducts multi-center studies to investigate the efficacy of novel blood tests and imaging techniques in identifying pancreatic cancer at an early stage. Their research aims to enhance patient outcomes through timely diagnosis and surveillance methods.
Peter A Calabresi — Dr. Peter A Calabresi’s research lab focuses on understanding how multiple sclerosis (MS) progresses and how we can predict its course in patients. By using advanced imaging techniques like MRI and optical coherence tomography, they study changes in the brain and retina that occur as MS advances. The goal is to develop better tools to monitor patients and guide treatment decisions, ultimately improving care for those with MS.
Jie Xiao — The research lab led by Jie Xiao at Johns Hopkins University focuses on understanding how bacteria manage essential processes like cell wall construction and chromosome organization. Using E. coli as a model organism, the team aims to uncover the molecular details that regulate these processes in living cells. They leverage advanced techniques such as single-molecule imaging and computational modeling to study the dynamics and interactions of proteins involved in these crucial cellular activities.
Laura Delong Wood — Dr. Laura Delong Wood's lab at Johns Hopkins University focuses on understanding how precancerous lesions in the pancreas evolve into cancer. By analyzing the genetics of these lesions and using advanced computational techniques, the lab aims to uncover the processes that lead to pancreatic cancer. This research hopes to pave the way for better early detection and treatment of pancreatic cancer by revealing crucial insights into its development.