Johns Hopkins University · BiologyWood Lab
Laura Delong Wood · Baltimore, Maryland
Research Focus
Dr. Laura Delong Wood's lab at Johns Hopkins University focuses on understanding how precancerous lesions in the pancreas evolve into cancer. By analyzing the genetics of these lesions and using advanced computational techniques, the lab aims to uncover the processes that lead to pancreatic cancer. This research hopes to pave the way for better early detection and treatment of pancreatic cancer by revealing crucial insights into its development.
pancreatic cancerprecancerous lesionsgenomic analysisRNA sequencingorganoid cultures
Research Aims
5AIM 01Characterize selective forces affecting the evolution of pancreatic precancerous lesions.
AIM 02Utilize genomic sequencing to identify molecular features of advanced subclones in IPMNs.
AIM 03Develop computational methods for integrating DNA and RNA sequencing data.
AIM 04Analyze organoid cultures to study selective pressures on pancreatic cells over time.
AIM 05Identify gene expression patterns in progressed clones using single-cell RNA sequencing.
Skills the Lab Values
DNA sequencingRNA sequencingcell culturemulti-omics integrationcomputational modelingthree-dimensional organoid systemsgenetic analysisdata integrationmolecular analysis
Output against the department
Publications583top 5% of dept.50th of 1,033
this lab
most publishedleast published
Citations51ktop 5% of dept.52nd of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.