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Wei Gao — The research lab led by Wei Gao focuses on developing innovative wearable technology for monitoring health, particularly in managing conditions like gout. They are creating a skin patch that can non-invasively measure uric acid levels in sweat, which can help patients make better dietary and medication choices. The lab also aims to understand how these measurements correlate with other metabolic conditions, enhancing patient care through improved adherence to treatment.
Scott Kevin Cushing — The Cushing lab at Caltech focuses on advancing methods in time-resolved fluorescence, which is essential for measuring biological signals with high precision. They are developing miniaturized devices that utilize entangled photon sources integrated with photonics technology, making portable medical diagnostics more accessible. Their work aims to improve health equity by allowing broader applications of these advanced measurement techniques in various biological and medical fields.
Mikhail Shapiro — Mikhail Shapiro's lab at Caltech focuses on developing cutting-edge techniques to control cellular behavior using ultrasound. This novel approach, called sonogenetics, aims to overcome limitations of traditional optical techniques by allowing researchers to manipulate cells deep within living tissues. The research has potential applications in neuroscience and cell therapy, helping advance our understanding of biological processes and improving treatment methods.
Linda C Hsieh-Wilson — Dr. Linda C Hsieh-Wilson's lab at Caltech is investigating the roles of chondroitin sulfate glycosaminoglycans (CS GAGs) in the brain, focusing on their structure, functions, and effects on neuroplasticity and inflammation. The research aims to understand how specific chemical modifications of CS GAGs influence processes that are crucial for memory, healing, and neurodegenerative diseases like Alzheimer's and multiple sclerosis. Students in the lab will engage in both chemistry and neurobiology techniques to explore these important interactions.
Shu-Ou Shan — Dr. Shu-Ou Shan's lab at Caltech focuses on understanding how proteins are made and folded correctly inside cells, which is essential for maintaining a healthy balance of proteins in our bodies. The research investigates specific processes like how proteins get chemical modifications while being formed and how helper proteins exist to guide these processes. By studying these intricate mechanisms, the lab aims to uncover why certain diseases occur when protein production goes wrong.
Athanassios Siapas — Dr. Athanassios Siapas leads a research lab focused on understanding how the hippocampus and dopamine influence memory formation. By investigating the interactions between different brain regions during learning, the lab aims to uncover how these processes can be disrupted in memory disorders like Alzheimer's disease. The research combines advanced imaging techniques with pharmacological and optogenetic tools to study memory at the circuit level.