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Md A Motaleb — Dr. Md A. Motaleb's lab at East Carolina University focuses on studying spirochetes, a group of bacteria responsible for serious diseases like Lyme disease and syphilis. The research aims to understand the unique flagellar proteins that enable these bacteria to move and cause disease. By investigating the molecular mechanisms of spirochete motility, the lab hopes to uncover new treatment strategies for infections caused by these pathogens.
Kwang Hun Lim — Dr. Kwang Hun Lim's lab focuses on understanding how certain metal ions cause the misfolding of a protein called transthyretin (TTR), which is related to serious diseases like ATTR amyloidosis. By studying how these proteins change structure and form toxic aggregates, the lab aims to find ways to prevent these harmful processes. This research is important because misfolded proteins can lead to a range of debilitating neurodegenerative disorders.
Adam Offenbacher — Dr. Adam Offenbacher's lab focuses on understanding the differences between two closely related blood proteins, fibrin and fibrinogen. They aim to explore how these proteins behave and transform in the body, particularly in relation to blood clotting and diseases like cardiovascular issues and Alzheimer's. By doing so, the lab hopes to develop targeted diagnoses and treatments based on the unique features of these proteins.