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Timothy J Trull — Dr. Timothy J. Trull's lab at the University of Missouri-Columbia focuses on understanding alcohol consumption patterns among young adults as they transition to legal drinking at age 21. Through the use of modern technology, including smartphones and breathalyzers, the lab investigates the contexts of drinking and behavioral consequences to inform better prevention and intervention strategies against alcohol use disorder.
Dongsheng Duan — Dr. Dongsheng Duan's research lab focuses on developing innovative gene therapies for Duchenne muscular dystrophy (DMD), a severe muscle-wasting condition. The lab employs advanced techniques like adeno-associated virus (AAV) delivery systems and CRISPR gene editing to enhance treatment efficacy and safety. By utilizing models, especially canines that closely mimic human DMD, they aim to refine therapeutic approaches and address challenges such as immune responses and treatment longevity.
Zheng Yan — Dr. Zheng Yan's lab at the University of Missouri-Columbia is focused on engineering innovative wearable devices for continuous cardiac monitoring. The lab is developing soft, skin-friendly biosensors that can accurately track both electrical and mechanical heart signals, even during physical activity. By enhancing device performance and user comfort, this research aims to improve early detection and treatment of heart diseases, ultimately benefiting patient outcomes and reducing healthcare costs.
Anthony Griffiths — Dr. Anthony Griffiths' research lab at the University of Missouri-Columbia focuses on infectious diseases and biocontainment, particularly concerning high-priority pathogens. The lab not only conducts cutting-edge research but also emphasizes the training of future scientists and professionals in dealing with emerging infectious diseases. Using state-of-the-art facilities, the lab aims to develop novel medical countermeasures and improve pandemic preparedness through collaboration and knowledge sharing in the field.
Michael S. Chapman — Dr. Michael Chapman's lab at the University of Missouri-Columbia focuses on improving gene therapy using adeno-associated viruses (AAV). They study how AAV interacts with host cells to better understand its entry process and develop more efficient gene delivery methods. Their research aims to design safer and more effective AAV vectors that can potentially treat various genetic diseases.
Christian L. Lorson — Dr. Christian L. Lorson's lab focuses on developing gene therapies for inherited neurological disorders, particularly Charcot-Marie-Tooth disease and related conditions. The lab works on creating animal models that mimic human diseases to understand the biological processes involved and to test potential therapeutic approaches. Ultimately, the goal is to develop effective treatments that can improve the quality of life for affected individuals.
Shi-Jie Chen — Dr. Shi-Jie Chen's laboratory focuses on developing new computational methods to model RNA structures, which is critical for advances in medicine such as vaccines and gene editing. The lab combines machine learning with biophysical techniques to tackle complex challenges in understanding how RNA functions and can be designed for therapeutic purposes. By analyzing vast amounts of RNA data, the lab aims to create tools that enhance the design of RNA-targeted therapies.
Luis A Martinez-Lemus — Dr. Luis A Martinez-Lemus leads a research lab focused on understanding how obesity contributes to cardiovascular disease, particularly through arterial stiffening and hypertension. The lab investigates the role of tissue transglutaminase, an enzyme that may be targeted to develop new therapies to improve vascular health and reduce heart disease risks in obese patients. By exploring the underlying mechanisms and testing pharmacological interventions, the lab aims to find innovative approaches to treat these conditions.
Kiho Lee — Dr. Kiho Lee's lab focuses on improving pigs as important models for both agriculture and human medicine by using advanced genome editing techniques like CRISPR. The research aims to enhance the safety and efficiency of creating genetically engineered pigs, which can help us better understand diseases and improve livestock traits. By developing new methods to quickly analyze these pigs after genetic modifications, the lab strives to make genetically edited pigs more accessible for scientific and agricultural purposes.