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Binghe Wang — Dr. Binghe Wang's lab at Georgia State University focuses on developing innovative therapies using carbon monoxide to treat acute kidney injury (AKI). The lab's research is significant because AKI is a common and serious condition with limited treatment options. By designing prodrugs that safely deliver carbon monoxide, the lab aims to enhance organ protection during and after injury, which could improve patient outcomes in medical settings.
Hang Shi — Dr. Hang Shi's lab at Georgia State University focuses on understanding how an enzyme called HDAC1 affects liver health and diseases, specifically non-alcoholic fatty liver disease (NAFLD), which is linked to obesity and diabetes. The research investigates how HDAC1 contributes to fat buildup and inflammation in the liver, potentially leading to severe liver complications. By exploring the relationship between diet and epigenetic changes in the liver, the lab aims to identify new therapeutic strategies for treating NAFLD.
Jianliang Xu — Dr. Jianliang Xu's lab focuses on developing innovative treatments for HIV using nanobodies, which are smaller and more versatile than traditional antibodies. The lab aims to create nanobodies that can target multiple sites on the HIV virus, potentially improving treatment effectiveness and simplifying administration. Their work could lead to breakthrough therapies that enhance the fight against AIDS and offer new hope for patients worldwide.
Ming Luo — Dr. Ming Luo's lab at Georgia State University focuses on understanding the assembly and structure of arenaviruses, such as the lymphocytic choriomeningitis virus (LCMV), which can pose serious public health threats. The team employs advanced techniques like cryo-electron tomography to visualize viral structures and explore how these pathogens assemble and interact at the molecular level. Their research aims to contribute to the development of vaccines and antiviral agents to combat viral outbreaks.
Cynthia A. Stappenbeck — Dr. Cynthia A. Stappenbeck's research focuses on preventing alcohol-facilitated intimate partner violence (IPV) among young adults. She is developing a mobile-based intervention that sends timely messages to individuals at risk, helping them manage their drinking and reduce the likelihood of IPV. This innovative approach uses real-time data to deliver personalized support during critical moments, aiming to improve safety and mental health outcomes.
Sierra E Carter — Dr. Sierra E. Carter's research lab focuses on understanding how stress during pregnancy impacts fetal development and health outcomes. By examining the daily stress experiences of pregnant women and assessing various biological indicators, the lab seeks to uncover ways to reduce health disparities in preterm birth and low birth weight outcomes. This research is particularly important for improving the well-being of mothers and infants in underserved communities.
Gennady S Cymbalyuk — Dr. Gennady Cymbalyuk's research lab investigates how the body senses cold and how this sensation can relate to pain, particularly in conditions like neuropathic pain and fibromyalgia. By using the fruit fly Drosophila as a model, the lab combines experiments with computer simulations to understand the basic biology of cold detection and its implications for health. This innovative approach not only explores the cellular and molecular side of cold sensing but also aims to shed light on how painful responses to cold develop in various diseases.