University of Alabama at Birmingham · BiochemistryLung Inflammation Research Laboratory
Natalia Y Kedishvili · Birmingham, Alabama
Research Focus
Dr. Natalia Kedishvili's lab focuses on understanding how specific enzymes influence inflammation in the lungs through their interactions with lipid mediators known as oxylipins. The research explores how the enzyme DHRS9 affects the balance between pro-inflammatory and anti-inflammatory signals, which is important for healing injuries and controlling inflammatory responses. By studying this enzyme, the lab aims to uncover potential new treatments for inflammatory diseases of the lungs.
oxylipin metabolisminflammationlung injuryDHRS9lipid mediators
Research Aims
4AIM 01Elucidate the molecular basis for DHRS9's broad substrate specificity.
AIM 02Identify the spectrum of natural substrates for DHRS9.
AIM 03Determine the physiological role of DHRS9 in lung inflammation and injury.
AIM 04Investigate the impact of DHRS9 deficiency on lung injury characteristics.
Skills the Lab Values
enzyme characterizationcell cultureflow cytometryWestern blotimmunoassay
Output against the department
Publications98bottom 24% of dept.307th of 402
this lab
most publishedleast published
Citations4.8kbottom 28% of dept.290th of 402
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.