University of North Carolina at Chapel Hill · ChemistryPeriodontal Innovation and Therapy Lab
Mark H Schoenfisch · Chapel Hill, North Carolina
Research Focus
Dr. Mark H Schoenfisch's lab focuses on developing innovative therapies to treat periodontal disease, a condition that causes inflammation and damage to the tissues supporting the teeth. The lab is working on creating a new type of treatment using hyaluronic acid that can release nitric oxide, which aims to fight harmful bacteria, reduce inflammation, and promote healing in the gums. Their research combines the fields of chemistry and biology to create effective, localized treatments for better oral and systemic health.
periodontal diseasehyaluronic acidnitric oxidebiofilm treatmentanti-inflammatory
Research Aims
3AIM 01synthesize nitric oxide-releasing hyaluronic acid for oral applications
AIM 02evaluate antibacterial effectiveness and safety of new formulations
AIM 03investigate the mechanisms behind microbial dysbiosis and tissue healing
Skills the Lab Values
synthesis of polymersin vitro cell culturemicrobial biofilm analysisdrug formulationin vivo testing
Output against the department
Publications277top 42% of dept.91st of 216
this lab
most publishedleast published
Citations17ktop 29% of dept.62nd of 216
this lab
most citedleast cited
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