Columbia University in the City of New York · EngineeringOrgan Development and Engineering Unit
Mijo Simunovic · New York, New York
Research Focus
The lab of Mijo Simunovic focuses on creating realistic models of human organ development using advanced techniques in stem cell biology and tissue engineering. They aim to understand how organs form by studying the gut tube and its neighboring organs, utilizing precise signaling methods to recreate the development process in the lab. Their innovative approaches may lead to new treatments and technologies for regenerative medicine and high-throughput drug screening.
organogenesisorganoidsstem cell biologytissue engineeringCRISPRmicrofluidicslive-cell microscopytranscriptomicsmorphogenesisregenerative medicine
Research Aims
5AIM 01Investigate the signaling networks involved in organ development
AIM 02Develop precise techniques for organoid formation
AIM 03Explore the relationship between signaling and morphogenesis
AIM 04Utilize CRISPR to control cell fate decisions
AIM 05Create a functional model of the gut tube organogenesis process
Skills the Lab Values
3D tissue cultureCRISPR gene editingmicrofluidicslive-cell imagingcellular assaystranscriptomic analysistissue micropatterningdata analysis with Pythonhigh-throughput screeningembryonic stem cell differentiation
Output against the department
Publications47bottom 6% of dept.261st of 278
this lab
most publishedleast published
Citations2.7kbottom 19% of dept.224th of 278
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.