Harvard University · Microbiology & ImmunologyThe Maternal Mind Lab
Jun R. Huh · Cambridge, Massachusetts
Research Focus
Dr. Jun R. Huh's lab at Harvard Medical School studies how pregnancy-related immune changes affect brain development in fetuses, particularly focusing on the differences between male and female brains. The research aims to understand why neurodevelopmental disorders, such as autism spectrum disorder, are more common in males and how maternal immune factors play a role in shaping fetal brain vulnerability to stress. By examining the mechanisms involved, the lab aims to provide insights that could lead to better interventions for these disorders.
neurodevelopmental disordersautism spectrum disorderfetal brain developmentmaternal immune activationsex-dependent differences
Research Aims
5AIM 01Investigate how maternal immune changes affect male versus female fetal brain development.
AIM 02Identify the molecular mechanisms behind increased male vulnerability to neurodevelopmental disorders.
AIM 03Examine sex-specific immune signaling in the placenta and its impact on fetal health.
AIM 04Analyze the role of interleukin-17 in neurodevelopmental outcomes based on fetal sex.
AIM 05Explore placental barrier functions in the context of prenatal inflammation.
Skills the Lab Values
rodent modelsimmunohistochemistrygene expression analysisplacenta isolationcytokine profiling
Output against the department
Publications101bottom 36% of dept.311th of 486
this lab
most publishedleast published
Citations13ktop 29% of dept.141st of 486
this lab
most citedleast cited
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