UTHThe University of Texas Health Science Center at Houston · Neuroscience
Mccullough Neurobiology Lab
Louise D. Mccullough · Houston, Texas
Research Focus
Dr. Louise D. Mccullough's lab focuses on understanding how sex and age affect the body's response to neurological conditions like stroke and COVID-19. The research aims to uncover biological differences that lead to varying outcomes in men and women, especially regarding inflammation and recovery. By investigating these differences, the lab hopes to develop targeted therapies to improve treatment for all patients affected by neurological diseases.
StrokeSex DifferencesInflammationNeuropsychiatric SymptomsCOVID-19Neural RepairCerebrovascular DisordersChronic InflammationTranslational Science
Research Aims
5AIM 01Investigate how sex differences influence inflammatory responses in neurological disorders.
AIM 02Examine the impact of age on inflammation and neural repair mechanisms after stroke.
AIM 03Identify sex-specific chronic effects of COVID-19 on neurologic health.
AIM 04Evaluate the role of the microbiome in sex differences related to inflammation.
AIM 05Develop novel therapeutic approaches based on findings regarding sex and age differences.
Skills the Lab Values
PCRCell CultureMouse ModelsFlow CytometryWestern BlotImmunohistochemistryRNA sequencingBiorepository ManagementData CollectionStatistical Analysis
Output against the department
Publications708top 7% of dept.47th of 671
this lab
most publishedleast published
Citations29ktop 14% of dept.91st of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.