WMCWeill Medical College of Cornell University · Biomedical Engineering
Vanpouille-Box Lab
Claire Isabelle Vanpouille-Box · New York, New York
Research Focus
Dr. Claire Isabelle Vanpouille-Box's lab studies glioblastoma, a challenging brain cancer, focusing on how radiation therapy affects tumor metabolism and immune responses. The lab investigates how glioblastoma cells change their metabolism to produce fatty acids and how this impacts the immune system, potentially leading to therapy resistance and tumor recurrence. By understanding these mechanisms, the research aims to find new ways to boost the immune response against these tumors after radiation treatment.
glioblastomaradiation therapyfatty acid metabolismtumor immunityimmune evasion
Research Aims
4AIM 01Investigate how radiation therapy alters glioblastoma metabolism.
AIM 02Determine the effect of fatty acids on immune system responses in glioblastoma.
AIM 03Explore mechanisms of immune evasion by glioblastoma cells after radiation.
AIM 04Test potential therapies that inhibit fatty acid production to enhance anti-tumor immunity.
Skills the Lab Values
cell cultureflow cytometrymouse modelsWestern blotRNA sequencing
Output against the department
Publications168bottom 38% of dept.369th of 595
this lab
most publishedleast published
Citations7.6ktop 46% of dept.272nd of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.