University of California-San Diego · Biomedical EngineeringCerebrospinal Fluid Dynamics Lab
Mitsue Miyazaki · La Jolla, California
Research Focus
Dr. Mitsue Miyazaki's lab at UC San Diego focuses on understanding how cerebrospinal fluid (CSF) drainage affects cognitive function, particularly in aging and Alzheimer's disease. The research aims to develop new non-invasive MRI techniques to measure CSF outflow and its connection to cognitive decline and physical activity. By studying these mechanisms, the lab hopes to contribute to early diagnosis and intervention strategies for neurodegenerative diseases.
Alzheimer's diseasecerebrospinal fluidglymphatic systemneurodegenerative diseaseMRI imagingcognitive declinephysical activityquantitative measures
Research Aims
4AIM 01Identify detailed pathways for cerebrospinal fluid egress in the brain.
AIM 02Obtain quantitative measures of CSF outflow from both brain hemispheres.
AIM 03Compare CSF outflow metrics in mild cognitive impairment and Alzheimer's patients with healthy adults.
AIM 04Investigate the influence of physical activity on CSF outflow metrics.
Skills the Lab Values
3D MRI imagingdata segmentation techniquesactigraphyquantitative analysisresearch designneurological assessmentsstatistical analysisliterature review
Output against the department
Publications116bottom 23% of dept.459th of 595
this lab
most publishedleast published
Citations3.0kbottom 22% of dept.463rd of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.