Icahn School of Medicine at Mount Sinai · GeneticsGut Microbiota and Inflammatory Bowel Disease Research Lab
Jeremiah James Faith · New York, New York
Research Focus
Dr. Jeremiah James Faith's lab focuses on understanding the role of gut microbiota in inflammatory bowel diseases (IBD) such as ulcerative colitis and Crohn's disease. They examine how these microbiota can be stable or transient in IBD patients and how this relates to disease progression and therapy effectiveness, particularly through methods like fecal microbiota transplantation (FMT). The research aims not only to illuminate the mechanisms of gut microbiome transmission and stability but also to explore new therapeutic strategies for IBD.
gut microbiotainflammatory bowel diseasefecal microbiota transplantationmetagenomicsmicrobial strain transmission
Research Aims
3AIM 01Investigate the stability of gut microbiota in individuals with inflammatory bowel disease over five years.
AIM 02Identify colitogenic and colitoprotective strains using gnotobiotic mouse models.
AIM 03Assess the implications of strain loss after fecal microbiota transplantation for long-term disease relapse.
Skills the Lab Values
metagenomicsfecal microbiota transplantationgnotobiotic mouse modelsmicrobial isolationhigh throughput sequencing