Yale University · Microbiology & ImmunologyNeutrophil Dynamics and Therapeutics Lab
Andres Hidalgo · New Haven, Connecticut
Research Focus
Dr. Andres Hidalgo's lab focuses on understanding the diverse roles of neutrophils in the immune system, particularly how different types of neutrophils can influence inflammation, immune response, and tissue repair. Their research explores how neutrophils, which are often known for their role in fighting infections, can also be involved in processes like promoting healing and modulating the adaptive immune system. By investigating these unique functions, the lab aims to uncover new ways to harness neutrophil activity for therapeutic benefit in diseases such as cancer and chronic inflammation.
neutrophilsinflammationimmune responsetissue repairimmunomodulationcancergranulopoiesisantigen presentation
Research Aims
5AIM 01Examine the origin and function of CX3CR1+ neutrophils and their unique properties compared to canonical neutrophils.
AIM 02Investigate the cytokines involved in the production of functionally distinct neutrophils and their role in health and disease.
AIM 03Assess the mechanisms through which neutrophils adapt to different tissue environments and contribute to tissue homeostasis.
AIM 04Define the angiogenic properties of neutrophils and their role in tissue repair, particularly in the lung.
AIM 05Explore how neutrophils acquire specialized functions in barrier tissues like the skin.
Skills the Lab Values
cell cultureflow cytometryRNA sequencingmouse modelsimmunofluorescenceWestern blotbiomechanical analysiscomputational modelingfate mappingin vivo imaging
Output against the department
Publications234top 26% of dept.127th of 486
this lab
most publishedleast published
Citations23ktop 16% of dept.77th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.