University of Connecticut · Biomedical EngineeringLiu Lab
Changchun Liu · Storrs, Connecticut
Research Focus
Dr. Changchun Liu's research lab focuses on developing innovative methods for HIV viral load testing using CRISPR technology. The lab aims to create a rapid and cost-effective diagnostic tool that can be used in resource-limited settings, addressing the urgent need for accessible HIV testing. This work combines advanced biomedical engineering techniques with molecular biology to improve public health outcomes related to HIV/AIDS.
HIVCRISPRdiagnostic toolsviral load testingmicrofluidics
Research Aims
5AIM 01Develop a rapid CRISPR-based method for HIV viral load testing.
AIM 02Evaluate the sensitivity and specificity of the new diagnostic tool.
AIM 03Integrate the assay into a microfluidic platform for ease of use.
AIM 04Validate the clinical application of the testing method with healthcare professionals.
AIM 05Investigate the mechanisms of CRISPR activation by various HIV RNA structures.
Skills the Lab Values
CRISPRmicrofluidicsRNA extractionfluorescence detectionbiological assay development
Output against the department
Publications150bottom 33% of dept.399th of 595
this lab
most publishedleast published
Citations6.3kbottom 48% of dept.312th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.