University of Kentucky · PharmacologyLiu Lab
Xiaoqi Liu · Lexington, Kentucky
Research Focus
Dr. Xiaoqi Liu's lab focuses on understanding and treating castration-resistant prostate cancer (CRPC). The research aims to identify new ways to combat the resistance that some prostate cancers develop against current therapies. By exploring various signaling pathways and potential biomarkers, the lab seeks to improve treatment options for patients who no longer respond to standard androgen signaling inhibitors.
prostate cancerandrogen signalingtherapeuticsbiomarkerscancer resistance
Research Aims
3AIM 01Identify new signaling pathways involved in castration-resistant prostate cancer.
AIM 02Evaluate the role of Plk1 in regulating tumor suppressor Pdcd4.
AIM 03Examine Wnt signaling's contribution to androgen signaling inhibitor resistance.
Skills the Lab Values
cell culturePCRbiochemical assaysmouse modelsRNA sequencingWestern blotgenetic manipulationpatient-derived xenograftsbioinformatics
Output against the department
Publications249top 32% of dept.149th of 462
this lab
most publishedleast published
Citations8.1ktop 46% of dept.212th of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.