University of Illinois Urbana-Champaign · EngineeringTargeted Therapeutics and Diagnostics Lab
Andrew Michael Smith · Champaign, Illinois
Research Focus
Dr. Andrew Smith's lab focuses on developing innovative delivery systems for cancer therapies and obesity management. They are particularly interested in using nanocarriers for targeted treatment of metastatic breast cancer and advancing blood-based diagnostics for prostate cancer. Their work aims to improve health outcomes through personalized medicine by harnessing the body’s immune responses and minimizing side effects.
drug deliverynanocarrierscancer immunotherapyobesitybiomarkersmicrofluidicsblood diagnosticsimmune modulationsignal transduction
Research Aims
5AIM 01Develop targeted nanocarriers for delivering immunotherapy to breast cancer tumors.
AIM 02Create a digital assay for analyzing cancer biomarkers from small blood samples.
AIM 03Design a drug depot for targeted delivery of obesity medications to improve patient adherence.
AIM 04Optimize combination therapies using immune modulators and nanocarrier technology.
AIM 05Evaluate the safety and effectiveness of engineered biomaterials in clinical settings.
Skills the Lab Values
nanoparticle synthesisdrug formulationcell culture techniquesflow cytometryWestern blotmicrofluidic device fabricationRNA isolationPCRexosome analysisdata interpretation
Output against the department
Publications742top 4% of dept.11th of 278
this lab
most publishedleast published
Citations21ktop 18% of dept.50th of 278
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.