Duke University · Biomedical EngineeringCollier Immunotherapy Lab
Joel H Collier · Durham, North Carolina
Research Focus
Dr. Joel Collier's lab at Duke University focuses on developing new types of treatments for chronic inflammatory diseases like inflammatory bowel disease and rheumatoid arthritis. Instead of using traditional antibody therapies that may not work for all patients, the lab designs innovative biomaterials that help the body's immune system generate its own healing responses. This involves creating smart materials that can help reduce inflammation and improve overall health outcomes with less frequent treatments.
biomaterialsimmunotherapynatural antibodiesinflammationchronic diseasessupramolecular assembliescomplement systemactive immunotherapy
Research Aims
4AIM 01Design biomaterials that engage the body's natural antibody responses to treat chronic inflammatory diseases.
AIM 02Develop supramolecular materials that can modulate the complement system to reduce harmful inflammation.
AIM 03Optimize delivery methods for innovative immunomodulatory treatments to improve patient compliance.
AIM 04Investigate the mechanisms of action of new immunotherapies in preclinical models of disease.
Skills the Lab Values
biomaterial synthesismouse modelsimmune response assessmentprotein engineeringdesign of supramolecular structuresin vitro cell culturepeptide chemistrydrug delivery methodsstatistical data analysis
Output against the department
Publications137bottom 28% of dept.427th of 595
this lab
most publishedleast published
Citations7.6ktop 45% of dept.270th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.