UTHThe University of Texas Health Science Center at Houston · Neuroscience
Stroke Recovery and Inflammation Unit
Anjali Chauhan · Houston, Texas
Research Focus
Dr. Anjali Chauhan's lab explores how biological and immune factors, particularly the IL6 signaling pathway, affect stroke recovery in older women. The research aims to uncover differences in recovery outcomes between sexes, specifically focusing on how inflammation and microglial signaling influence brain injury and cognitive decline following strokes. The goal is to provide insights that could lead to better, sex-specific treatments for stroke survivors.
ischemic strokeinflammationIL6 signalingsex differencescognitive declinemicrogliavascular contributionsAlzheimer's diseasetherapeutics
Research Aims
3AIM 01Investigate the role of IL6/IL6R signaling in long-term recovery after ischemic stroke in females.
AIM 02Determine how the second X chromosome influences IL6/IL6R signaling in aged females.
AIM 03Assess microglial IL6/IL6R trans-signaling effects on neuroinflammation and cognitive outcomes post-stroke.
Skills the Lab Values
microglial cultureflow cytometrymouse modelsELISAgene editingimmunohistochemistryWestern blotnervous system assessmentsbehavioral testingconfocal microscopy
Output against the department
Publications198top 37% of dept.249th of 671
this lab
most publishedleast published
Citations2.8kbottom 18% of dept.548th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.