Texas A&M University-College Station · BiologySleep Genetics and Disorders Lab
Alex C Keene · College Station, Texas
Research Focus
Dr. Alex C Keene's lab at Texas A&M University focuses on understanding the genetics of sleep regulation and its implications for sleep disorders like insomnia. The research combines genetic analysis, animal models, and behavioral studies to identify how specific genes and molecular pathways affect sleep patterns in humans and model organisms. The ultimate goal is to elucidate the biological mechanisms behind sleep-related genetic variations, which could lead to better diagnosis and treatment for sleep disorders.
sleep geneticsinsomniaGPI-anchor biosynthesishuman GWASanimal models
Research Aims
5AIM 01Investigate the role of GPI-anchor biosynthesis in sleep regulation.
AIM 02Identify genetic variants associated with sleep disorders.
AIM 03Functionally validate sleep-related genes using animal models.
AIM 04Map the effects of insomnia risk genes on sleep patterns.
AIM 05Understand molecular mechanisms underlying sleep regulation in humans.
Skills the Lab Values
genomic computational analysisbehavioral assaysDrosophila geneticsgene expression profilingRNA interferencemolecular cloning
Output against the department
Publications251top 24% of dept.248th of 1,033
this lab
most publishedleast published
Citations8.3ktop 46% of dept.474th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.