Yale University · Biomedical EngineeringHuang Lab
Yiyun Henry Huang · New Haven, Connecticut
Research Focus
Dr. Yiyun Henry Huang's lab at Yale University focuses on understanding and diagnosing Alzheimer's disease using advanced imaging techniques. The lab is particularly interested in the sigma-1 receptor, which plays a crucial role in the disease's progression. By developing new PET imaging agents, the lab aims to uncover important biomarkers that could lead to earlier diagnosis and better monitoring of disease treatments.
Alzheimer's Diseasesigma-1 receptorPET imagingbiomarkersdisease progression
Research Aims
5AIM 01Develop and validate a novel PET imaging agent for Alzheimer's disease.
AIM 02Investigate the role of the sigma-1 receptor in Alzheimer's pathogenesis.
AIM 03Explore longitudinal changes in synaptic markers in Alzheimer's animal models.
AIM 04Identify biomarkers for the early diagnosis of Alzheimer's disease.
AIM 05Monitor the progression of Alzheimer's disease and treatment effects.
Skills the Lab Values
PET radioligand developmentanimal model studiesbiomarker analysissynthetic chemistryimaging techniques
Output against the department
Publications368top 25% of dept.146th of 595
this lab
most publishedleast published
Citations11ktop 32% of dept.188th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.