University of California-Davis · BiologyGene Editing Safety and Immunoassay Unit
Alice F Tarantal · Davis, California
Research Focus
Dr. Alice F. Tarantal's research focuses on improving safety in gene editing therapies by developing precise immunoassays that can evaluate immune responses to these treatments. Her work aims to validate sensitive tests that assess the interaction of the immune system with gene editing tools used in clinical trials. Ultimately, her lab strives to ensure that these innovative therapies are safe and effective for human use.
gene editingimmunoassaysclinical trialscytokine analysissafety monitoring
Research Aims
5AIM 01Validate flow cytometry assays to measure T-cell immunity to gene editing vectors.
AIM 02Develop multiplex assays for detecting binding antibodies to gene editing proteins.
AIM 03Characterize immune responses to gene editors in vivo using PET imaging.
AIM 04Ensure accuracy and reliability of assays for regulatory compliance in clinical studies.
AIM 05Provide tools that facilitate the transition of gene editing therapies to clinical applications.
Skills the Lab Values
flow cytometrymultiplex immunoassaysPET imagingT-cell isolationimmune response assessment
Output against the department
Publications204top 32% of dept.332nd of 1,033
this lab
most publishedleast published
Citations8.5ktop 45% of dept.462nd of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.