Northwestern University · BiologyHair Stem Cell Dynamics Lab
Rui Yi · Evanston, Illinois
Research Focus
Dr. Rui Yi's lab at Northwestern University focuses on understanding how hair follicle stem cells function and age. The lab investigates the mechanical properties and the genetic regulation of these stem cells, exploring how they respond to their surrounding environment. By using advanced imaging and genetic tools, the research aims to uncover new insights into hair growth and potential treatments for age-related hair loss.
hair follicle stem cellscell mechanicsagingextracellular matrixmicroRNA-205mechanotransductionregenerative medicinesingle-cell genomicsintravital imaging
Research Aims
3AIM 01Investigate the role of miR-205 in regulating hair follicle stem cell activation during aging.
AIM 02Determine how PIEZO1-mediated mechanosensing affects hair follicle stem cells.
AIM 03Explore the genetic control of hair follicle stem cell maintenance and their niche during different hair cycle stages.
Skills the Lab Values
cell culturemouse modelsRNA sequencinghigh-resolution imaginggenetic engineeringintravital imagingmicroRNA analysiscalcium imagingtranscription factor analysis
Output against the department
Publications88bottom 29% of dept.733rd of 1,033
this lab
most publishedleast published
Citations8.6ktop 44% of dept.454th of 1,033
this lab
most citedleast cited
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