Johns Hopkins University · NeuroscienceNeurosarcoidosis Research Laboratory
Carlos A Pardo-Villamizar · Baltimore, Maryland
Research Focus
Dr. Carlos A Pardo-Villamizar's lab at Johns Hopkins University focuses on understanding neurosarcoidosis, a condition that affects the nervous system and arises from a systemic inflammatory disorder. The research aims to identify specific biomarkers and immune profiles linked to the disease, explore the role of genetic signatures, and uncover potential antigens or pathogens that may trigger the inflammatory response. This work seeks to better characterize patient phenotypes and improve therapeutic strategies for neurosarcoidosis.
NeurosarcoidosisBiomarkersImmune profilesGene expressionNeuroinflammationCerebrospinal fluidMolecular immunologyAntibody responsePathogensClinical phenotypes
Research Aims
3AIM 01Characterize clinical phenotypes of neurosarcoidosis patients using biological samples.
AIM 02Identify immune profiles and gene expression signatures associated with neurosarcoidosis.
AIM 03Determine the presence of antibodies to host and microbial antigens related to neurosarcoidosis.
Skills the Lab Values
Cerebrospinal fluid analysisMolecular profilingRNA sequencingImmunoprecipitationClinical data collectionCytokine analysisPhenotyping of patientsPhage display techniquesData interpretationImmunological assays