Case Western Reserve University · Biomedical EngineeringFlask MRI Lab
Christopher A Flask · Cleveland, Ohio
Research Focus
Dr. Christopher Flask's lab focuses on improving cancer diagnosis and treatment monitoring using advanced MRI techniques. By developing innovative methods such as Magnetic Resonance Fingerprinting (MRF), they aim to better measure tumor blood flow and acidity. Their research highlights the potential for these techniques to be translated into clinical settings for more effective cancer therapies.
Magnetic Resonance Fingerprintingtumor vascular perfusionextracellular pHcancer imagingdynamic contrast-enhanced MRIMRI contrast agentspreclinical modelsradiotherapycancer therapydiagnostic imaging
Research Aims
5AIM 01Optimize a 3D T1-MRF method to evaluate tumor vascular perfusion in mouse models.
AIM 02Develop a two-agent MRF method to measure extracellular pH in tumors.
AIM 03Monitor changes in tumor pH after therapeutic treatments using MRI techniques.
AIM 04Validate the precision of DCE-MRF compared to standard DCE-MRI methods.
AIM 05Translate innovative imaging methods for clinical use in cancer patients.
Skills the Lab Values
Magnetic Resonance Imaging (MRI)dynamic contrast enhancementmouse cancer modelsquantitative imagingimage analysiscontrast agent administration3D imaging techniquesexperimental designdata processingbiostatistics
Output against the department
Publications250top 39% of dept.234th of 595
this lab
most publishedleast published
Citations8.1ktop 43% of dept.254th of 595
this lab
most citedleast cited
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