Virginia Commonwealth University · Microbiology & ImmunologyPathogen Immunity Lab
Jason A Carlyon · Richmond, Virginia
Research Focus
Dr. Jason Carlyon's lab at Virginia Commonwealth University studies serious diseases caused by two bacterial pathogens: Orientia tsutsugamushi, which leads to scrub typhus, and Anaplasma phagocytophilum, which causes human granulocytic anaplasmosis. By understanding how these pathogens interact with host immune systems and cells, the lab aims to develop new treatment strategies and enhance our knowledge of microbial infections.
scrub typhusAnaplasma phagocytophilumhost-pathogen interactionsbacterial pathogenesisimmune modulation
Research Aims
3AIM 01Investigate how Orientia tsutsugamushi's ankyrin repeat proteins inhibit immune responses.
AIM 02Identify the mechanisms of Anaplasma phagocytophilum surface proteins in promoting infection.
AIM 03Characterize the effects of ceramide in Anaplasma phagocytophilum pathogenesis.
Skills the Lab Values
molecular biology techniquescell cultureimmunofluorescenceprotein purificationWestern blot analysis
Output against the department
Publications101bottom 36% of dept.310th of 486
this lab
most publishedleast published
Citations3.0kbottom 21% of dept.385th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.