EUEmory University · Chemistry
Antibiotic Resistance Research Lab
Christine M Dunham · Atlanta, Georgia
Research Focus
Dr. Christine M. Dunham's lab focuses on understanding how certain bacteria, especially Pseudomonas aeruginosa, resist antibiotics through specialized mechanisms. They study a particular group of proteins called RND efflux pumps, which help these bacteria expel antibiotics and survive in challenging environments. The research aims to uncover the genetic and molecular processes behind this resistance, paving the way for better treatments against difficult bacterial infections.
antibiotic resistanceefflux pumpsPseudomonas aeruginosagene regulationbacterial genetics
Research Aims
4AIM 01Uncover novel aspects of P. aeruginosa physiology related to antibiotic treatment.
AIM 02Define the molecular processes leading to the expression of antibiotic efflux pumps.
AIM 03Investigate the structure and function of the MexXY-OprM transporter system.
AIM 04Discover strategies for developing new antibiotics against resistant bacterial strains.
Skills the Lab Values
cell culturemicrobial geneticsstructural biologycomputational biologyprotein expression and purification
Output against the department
Publications181bottom 42% of dept.125th of 216
this lab
most publishedleast published
Citations4.6kbottom 35% of dept.141st of 216
this lab
most citedleast cited
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