Virginia Commonwealth University · PharmacologyCenter for Ocular Injury Research
Qingguo Xu · Richmond, Virginia
Research Focus
Dr. Qingguo Xu's lab is focused on developing innovative treatments for eye injuries caused by chemical exposure, specifically nitrogen mustard. The lab is working on a special eyedrop formulation that includes fenofibrate, a drug known for its anti-inflammatory properties, aiming to facilitate healing of corneal injuries. Their research includes testing the effectiveness of these eyedrops in animal models, as well as ensuring they are safe for use in humans.
fenofibratecorneal injurymicroemulsionPPARanti-inflammatoryocular treatmentneovascularization
Research Aims
4AIM 01Develop a fenofibrate-loaded microemulsion eyedrop for corneal injury.
AIM 02Validate PPAR signaling as a therapeutic target.
AIM 03Test the efficacy of the eyedrop solution in rabbit models.
AIM 04Establish a corneal wound model in minipigs for future studies.
Skills the Lab Values
eyedrop formulationanimal modelsdrug delivery systemspharmacokineticsin vivo studiescorneal wound healingstability testingbioassays
Output against the department
Publications117bottom 33% of dept.309th of 462
this lab
most publishedleast published
Citations12ktop 32% of dept.146th of 462
this lab
most citedleast cited
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