The University of Texas at San Antonio · EngineeringGiambini Lab
Hugo Giambini · San Antonio, Texas
Research Focus
Dr. Hugo Giambini's lab focuses on improving recovery from rotator cuff tears, a common shoulder injury that can lead to muscle degeneration. They are developing innovative nanotherapy approaches to convert unhealthy fatty tissue into a healthier, metabolically active type of fat, which could enhance muscle healing and function after injuries. By blending engineering techniques with biological insights, the lab aims to find effective treatments for better patient outcomes in shoulder injuries.
nanotherapyrotator cuff tearsfatty infiltrationmuscle regenerationadipose tissuebrown fatthermogenesisin vivo modelsinjury repair
Research Aims
3AIM 01Optimize the design of lipid-coated nanoparticles for better delivery and fat browning.
AIM 02Investigate the effects of brown adipose tissue on muscle cell performance in vitro.
AIM 03Determine the functional and regenerative effects of the novel nanotherapy in in vivo rotator cuff tear models.
Skills the Lab Values
nanotechnologycell cultureanimal modelsfatty tissue analysisdrug delivery systemsin vitro studiesgene expression techniquesmicroscopybiomarker assessment
Output against the department
Publications81bottom 15% of dept.235th of 278
this lab
most publishedleast published
Citations1.5kbottom 11% of dept.248th of 278
this lab
most citedleast cited
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