The University of Texas Health Science Center at San Antonio · BiochemistryTriple-Negative Breast Cancer Therapeutics Lab
Jean X Jiang · San Antonio, Texas
Research Focus
Dr. Jean X Jiang's lab focuses on developing innovative treatments for triple-negative breast cancer (TNBC), an especially aggressive form of breast cancer that disproportionately affects younger patients and women of color. The lab is working on creating novel drugs that target adenosine receptors to inhibit tumor growth and enhance anti-tumor immunity. By employing advanced technologies in drug design and testing in animal models, the aim is to generate effective therapies that improve the survival of patients with this challenging disease.
triple-negative breast canceradenosine receptorsinverse agonistsdrug discoverytumor growth inhibition
Research Aims
3AIM 01Develop novel adenosine receptor inverse agonists for TNBC treatment
AIM 02Optimize drug properties using AI-based drug discovery
AIM 03Evaluate the efficacy of drug candidates in mouse models
Skills the Lab Values
cell culturemouse modelsdrug developmentmedicinal chemistryin vitro testing
Output against the department
Publications297top 21% of dept.86th of 402
this lab
most publishedleast published
Citations16ktop 28% of dept.114th of 402
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.