University of Pittsburgh-Pittsburgh Campus · BiologySinghi Lab
Aatur Dilip Singhi · Pittsburgh, Pennsylvania
Research Focus
Dr. Aatur Dilip Singhi's lab at the University of Pittsburgh focuses on understanding non-functional pancreatic neuroendocrine tumors (NF-PanNETs), which are complex and varied tumors that can behave aggressively. The research aims to identify new biomarkers that can help predict how these tumors grow and spread. By studying the genetic and epigenetic changes that occur in these tumors, the lab hopes to improve patient outcomes through better prognostic tools and understanding of tumor behavior.
pancreatic tumorschromatin remodelingbiomarkersgenomic alterationsepigenetics
Research Aims
3AIM 01Develop and validate prognostic biomarker assays for NF-PanNETs.
AIM 02Characterize chromatin patterns in metastatic progression of NF-PanNETs.
AIM 03Investigate the adaptive response of ATRX/DAXX inactivation and ALT initiation.
Skills the Lab Values
DNA sequencingmolecular biology techniquesRNA sequencingcell culturechromatin analysis techniques
Output against the department
Publications705top 3% of dept.34th of 1,033
this lab
most publishedleast published
Citations17ktop 23% of dept.241st of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.