Harvard University · BiologyProteomics and Systems Biology Lab
Steven P Gygi · Cambridge, Massachusetts
Research Focus
Dr. Steven P Gygi's lab at Harvard Medical School focuses on innovative techniques for studying proteins, which are crucial molecules in biological processes. His research aims to improve methods for analyzing protein levels and modifications in various conditions, helping to define protein functions and discover potential therapies for diseases. The lab is particularly known for advancing sample multiplexing technologies that allow for efficient analysis of multiple protein samples simultaneously.
proteomicsmass spectrometrysample multiplexingprotein modificationschemical biology
Research Aims
5AIM 01Develop advanced mass spectrometry technologies for protein analysis.
AIM 02Enhance sample multiplexing capacity to accommodate more samples.
AIM 03Create real-time management software for proteome analysis.
AIM 04Design workflows for identifying small molecule-protein interactions.
AIM 05Investigate the role of post-translational modifications in protein function.
Skills the Lab Values
mass spectrometryisobaric taggingdata analysis with custom softwareproteome analysistargeted sample multiplexing
Output against the department
Publications1,040top 1% of dept.14th of 1,033
this lab
most publishedleast published
Citations172ktop 1% of dept.2nd of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.