Massachusetts Institute of Technology · EngineeringInnovative mRNA Vaccine Lab
Daniel G Anderson · Cambridge, Massachusetts
Research Focus
Professor Daniel G. Anderson's research lab at MIT focuses on developing innovative mRNA vaccines for HIV. By combining cutting-edge computational design with biomedical engineering, the lab aims to create vaccines that can elicit a strong immune response, producing broadly neutralizing antibodies that can adapt to various strains of the virus. The lab's work is crucial for addressing the ongoing challenges in creating effective HIV vaccines, with the potential to significantly impact public health.
mRNA vaccinesHIVbroadly neutralizing antibodiesantigen deliveryimmune response
Research Aims
5AIM 01Develop computationally designed mRNA vaccines to target HIV.
AIM 02Engineer lipid nanoparticles for effective antigen delivery.
AIM 03Optimize immunization protocols to enhance immune response.
AIM 04Conduct preclinical assessments of vaccine efficacy in animal models.
AIM 05Investigate the role of germinal centers in antibody response.
Skills the Lab Values
mRNA synthesislipid nanoparticle formulationanimal modelscomputational modelingimmunization protocolscell cultureflow cytometryantibody titer measurement
Output against the department
Publications466top 13% of dept.35th of 278
this lab
most publishedleast published
Citations66ktop 3% of dept.9th of 278
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.