Icahn School of Medicine at Mount Sinai · Biomedical EngineeringXiang Lab
Xiang Xu · New York, New York
Research Focus
Dr. Xiang Xu's research lab focuses on understanding the neurological aspects of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), particularly in patients who have experienced long-term effects after COVID-19, known as Post-Acute Sequelae of SARS-CoV-2 infection (PASC). The lab utilizes advanced imaging techniques to investigate how brain metabolism and circulation differ between PASC patients and those with classic ME/CFS. This research aims to uncover potential shared mechanisms underlying these conditions, which may open up new avenues for diagnosis and treatment.
long COVIDME/CFSbrain metabolismcerebral imagingglucose metabolismchronic fatigue syndromepost-viral syndromepatient outcomes
Research Aims
4AIM 01Investigate differences in cerebral oxygen and glucose metabolism between PASC and non-PASC ME/CFS patients.
AIM 02Measure and compare cerebral blood flow and metabolic rates in patients and healthy controls.
AIM 03Correlate MRI-derived metabolic parameters with patient symptom burden.
AIM 04Conduct follow-up studies on metabolic changes in PASC patients over time.
Skills the Lab Values
Magnetic Resonance Imaging (MRI)Cerebral blood flow measurementMetabolic rate analysisStatistical data analysisClinical patient assessmentsComparative analysis techniquesLongitudinal study designPatient-reported outcomes evaluation
Output against the department
Publications478top 17% of dept.101st of 595
this lab
most publishedleast published
Citations11ktop 31% of dept.187th of 595
this lab
most citedleast cited
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