Yale University · GeneticsThe Neuron Nexus
Marc Hammarlund · New Haven, Connecticut
Research Focus
Marc Hammarlund's lab at Yale University focuses on understanding how different types of neurons in the worm C. elegans use gene expression to develop and function. They study how these neurons differ from each other at various stages of growth, including how they express genes in male and female forms. By mapping out gene expression and splicing patterns, the lab aims to uncover the complex genetic mechanisms behind neuronal diversity, which could provide insights into human neurological conditions.
C. elegansgene expressionneuronal diversitysplicing patternsneurogenetics
Research Aims
4AIM 01Build a comprehensive gene expression atlas for all C. elegans neurons at different developmental stages.
AIM 02Identify sexually dimorphic gene expression between male and female neurons.
AIM 03Characterize splicing patterns in all neuron types.
AIM 04Develop analytical tools and share data with the scientific community.
Skills the Lab Values
RNA sequencinggene expression profilingdata analysisbioinformaticscell lineage tracing
Output against the department
Publications89bottom 26% of dept.192nd of 259
this lab
most publishedleast published
Citations5.0kbottom 28% of dept.187th of 259
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.