University of Michigan-Ann Arbor · ChemistryRNA Structure and Function Lab
Nils G Walter · Ann Arbor, Michigan
Research Focus
Dr. Nils G. Walter's lab at the University of Michigan focuses on understanding how RNA molecules control gene expression through their unique structures and behaviors. By using advanced microscopy techniques, the lab investigates RNA nanomachines, unraveling their roles in regulating transcription and translation in cells. This research has broad implications for biological processes and can lead to discoveries that reshape our understanding of gene regulation.
RNA nanomachinesgene expressionsingle molecule fluorescencetranscription regulationRNA folding
Research Aims
5AIM 01Investigate the mechanisms of RNA nanomachines involved in gene expression.
AIM 02Explore the structural and kinetic properties of RNA during transcription and translation.
AIM 03Examine the impact of riboswitches on transcriptional regulation.
AIM 04Push the technical limits of single-molecule approaches to address complex biological questions.
AIM 05Uncover new RNA functions that influence gene regulation.
Skills the Lab Values
single-molecule fluorescence microscopyenzymatic biochemistryRNA chemical synthesiscell extracts reconstitutiondata analysis with Python
Output against the department
Publications390top 28% of dept.59th of 216
this lab
most publishedleast published
Citations14ktop 35% of dept.75th of 216
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.