University of Virginia-Main Campus · Biomedical EngineeringJanes Lab
Kevin A Janes · Charlottesville, Virginia
Research Focus
Dr. Kevin A. Janes' research lab at the University of Virginia focuses on understanding viral infections and their impact on human health, specifically through innovative computational models and genetic analyses. They also explore the origins and progression of basal-like breast cancer, which is known for its aggressive nature and poor prognosis. By combining advanced modeling techniques with genetically engineered mouse models, the lab aims to uncover critical insights into both viral and cancer biology.
RNA virusesbasal-like breast cancercomputational modelinggenetically engineered mouse modelscell-state variabilityimmune responsetherapeutic interventionviral life cycle
Research Aims
4AIM 01Evaluate modeling strategies for understanding subcellular infection by RNA viruses.
AIM 02Identify cellular and molecular transitions leading to basal-like breast cancer.
AIM 03Investigate immune interactions within premalignant lesions of breast cancer.
AIM 04Develop therapeutic strategies based on cellular plasticity and immune diversity.
Skills the Lab Values
computational modelingmouse modelstranscriptomicsviral entry analysisgenetic engineeringbioinformaticsimmunologydata analysiscell culture
Output against the department
Publications178bottom 41% of dept.353rd of 595
this lab
most publishedleast published
Citations8.0ktop 43% of dept.257th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.