New York University · ChemistryNoncoding RNA Dynamics Lab
Alisha Jones · New York, New York
Research Focus
Alisha Jones's lab at New York University focuses on understanding how long noncoding RNAs (lncRNAs) change their shape and how these changes affect their biological functions. The team studies the processes of lncRNA splicing and aims to uncover the molecular mechanisms by which these RNA molecules regulate important biological processes, including gene silencing. By integrating research with a hands-on training program for students of all levels, the lab prepares future scientists to explore the therapeutic potential of lncRNAs in disease.
lncRNAstructural biologyRNA splicinggene silencingtherapeutic targeting
Research Aims
5AIM 01Investigate how lncRNA structural dynamics determine their function.
AIM 02Identify regulatory factors involved in lncRNA splicing.
AIM 03Map the energy landscapes of lncRNA structural states.
AIM 04Explore the link between lncRNA conformation and protein binding.
AIM 05Develop therapeutic strategies targeting lncRNAs implicated in disease.
Skills the Lab Values
RNA isolationPCRgel electrophoresismolecular cloningstructural analysiscomputational modelingcell culturebioinformaticssequencing
Output against the department
Publications49bottom 8% of dept.198th of 216
this lab
most publishedleast published
Citations717bottom 5% of dept.205th of 216
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.