UMCUniversity of Massachusetts Chan Medical School · Biology
The Regenerative Genetics Lab
Victor Ambros · Worcester, Massachusetts
Research Focus
Dr. Victor Ambros's lab focuses on how genetic networks control when and how an organism develops. They study tiny worms, like C. elegans, to understand the role of microRNAs in helping these organisms adapt to stresses during their growth. Their research also explores how certain worms can regenerate their bodies, offering insights into the biology of regeneration across species.
developmental timingmicroRNAsCaenorhabditis elegansstress resiliencetissue regenerationgenetic regulatory networkswhole-body regenerationpost-transcriptional regulationheterochronic genes
Research Aims
5AIM 01Study how genetic regulatory networks control developmental timing in animals.
AIM 02Investigate the role of microRNAs in stress resilience during development.
AIM 03Explore the mechanisms of whole-body regeneration in the worm Hofstenia miamia.
AIM 04Characterize the interaction between microRNAs and RNA-binding proteins.
AIM 05Advance understanding of heterochronic genes in developmental processes.
Skills the Lab Values
RNA extractionPCRgene expression analysismicroRNA profilingC. elegans worktissue cultureregeneration assaysbioinformaticsdevelopmental biology techniques
Output against the department
Publications167top 40% of dept.409th of 1,033
this lab
most publishedleast published
Citations54ktop 4% of dept.44th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.